Gatenby, R. A., & Gawlinski, E. T. (2003). The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models. Cancer research, 63(14), 3847-3854. Las células malignas exhiben característicamente patrones metabólicos alterados…
Gatenby, R. A., & Gillies, R. J. (2004). Why do cancers have high aerobic glycolysis?. Nature reviews cancer, 4(11), 891. Si la carcinogénesis ocurre por evolución somática, los componentes comunes del fenotipo…
Li, N., Tan, W., Li, J., Li, P., Lee, S., Wang, Y., & Gong, Y. (2011). Glucose metabolism in breast cancer and its implication in cancer therapy. International Journal of Clinical Medicine,…
Mathupala, S. P., Rempel, A., & Pedersen, P. L. (1997). Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical…
Mathupala, S. P., Heese, C., & Pedersen, P. L. (1997). Glucose catabolism in cancer cells the type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53. Journal of…
Hay, N. (2016). Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?. Nature Reviews Cancer, 16(10), 635. En los últimos años ha habido un creciente interés entre los biólogos del…
Gitenay, D., Wiel, C., Lallet-Daher, H., Vindrieux, D., Aubert, S., Payen, L., … & Bernard, D. (2014). Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence. Cell death & disease, 5(2), e1089. La…
Eizirik, D. L., Colli, M. L., & Ortis, F. (2009). The role of inflammation in insulitis and β-cell loss in type 1 diabetes. Nature Reviews Endocrinology, 5(4), 219. La diabetes…
Giacco, F., & Brownlee, M. (2010). Oxidative stress and diabetic complications. Circulation research, 107(9), 1058-1070. El estrés oxidativo desempeña un papel fundamental en el desarrollo de complicaciones de la diabetes,…
Folkers, K., Langsjoen, P., Willis, R., Richardson, P., Xia, L. J., Ye, C. Q., & Tamagawa, H. (1990). Lovastatin decreases coenzyme Q levels in humans. Proceedings of the National Academy of Sciences,…